21/01/06
              Gene markers which influence traits like meat tenderness and
                carcase quality are set to become a main stream breeding tool,
                north pedigree and commercial beef farmers were told at a meeting
                in Carlisle.
              
               
              Extensively used in other livestock producing countries, including
                the US, France and New Zealand, Merial Animal Health's
                Igenity testing service brought gene markers, which identify
                specific genetic traits, to the UK and the meeting in Carlisle
                at the Shepherd's Inn on Wednesday (January 18) was its
                first main introduction to breeders. 
              Held in conjunction with leading pedigree auctioneers Harrison & Hetherington
                who invited both pedigree and commercial beef farmer clients
                to the meeting, it was attended by around 50 people. 
              Igenity's head in Europe, Nigel Otter told the meeting: “Gene
                markers are becoming a main stream breeding tool in the UK. 
              “They are being used extensively in other countries - for
                example France has a major programme evaluating the genes involved
                in meat eating quality. In the States, where it is also widely
                used, sale catalogue entries are backed up by gene markers.” 
              Mr Otter said while until now beef breeders had only been able
                to select for traits such as growth rates and leaner, more muscled
                carcases, now this new science enabled them to be able to breed
                specifically for the eating quality of the animal's carcase. 
              The naturally occurring protein calpain influences meat tenderness
                post-mortem by weakening muscle fibres and the test identifies
                variations in animals' calpain genotype, rated on a scale
                of one to five on their ability to produce tender meat. 
              “Meat tenderness excites the supermarkets and it is the
                number one priority for beef. They want to improve the quality
                of the eating experience and they want this quality to be much
                more reliable and consistent. In this way gene markers for beef
                will have influence throughout the food chain, particularly amid
                competition from tender meats such as chicken,” said Mr
                Otter. 
              The gene marker for carcase quality identifies the protein leptin
                which influences feed intake and fat deposition, and it further
                enhance information already available on levels of fat deposits,
                carcase weight and rib eye size. 
              Knowing an animal's leptin genotype allows breeders to
                make more informed management decisions regarding breeding, nutrition
                and management. 
              Much of the work in the field of gene markers for beef cattle
                has been carried out in the US, in particular at one of the main
                beef reference establishments in the world, the Meat Animal Research
                Centre in Nebraska. 
              Igenity with the National Beef Association has carried out a
                study - as yet unpublished - with six UK pedigree beef
                cattle societies, funded by Genesis Faraday in Edinburgh, to
                look at tenderness and carcase traits. 
              During the last year Igenity has carried out 2,000 of the tests
                in the UK which by DNA fingerprinting gives breeders access to
                the genetic make-up of their cattle, allowing more objective
                breeding decisions to be made. 
              Mr Otter said the test simply involved taking a few strands
                of the animal's tail hairs. The DNA is then extracted from
                the hair follicles in the laboratory and is then analysed for
                the presence of gene markers. 
              Kits of 10 tests cost £30 per animal. The ideal would
                be to test the top two thirds of both males and females in a
                pedigree beef herd. 
              Igenity has its store set on a panel of up to 90 different gene
                markers which would include meat traceability from farm to plate. 
              “For breeders it's going to be an important marketing
                tool - for both pedigree and commercial producers. If supermarkets
                and leading retailers are prepared to pay a premium for tenderness,
                then there's a big incentive for breeders to use it,” said
                Mr Otter. 
              “By selecting for superior tenderness breeders can make
            very fast progress over two generations,” he added. 
               
               * Merial is a world-leading, innovation-driven animal health
                company, providing a comprehensive range of products to enhance
                the health, well-being and performance of a wide range of animals.
                Merial employs approximately 5,000 people and operates in more
                than 150 countries worldwide. Its 2004 sales were in excess of
                $1.8 billion. Merial Limited is
            a joint venture between Merck & Co., Inc. and sanofi-aventis.
            For more information, please see www.merial.com  
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